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| | <span style="display:none">forresearchers</span> |
| | <span style="display:none">forpatients</span> |
| | <span style="display:none">forproviders</span> |
| | <span style="display:none">forpolicymakers</span> |
| | <span style="display:none">estoniacountry</span> |
| | <span style="display:none">isCancerCenter</span> |
| [https://wiki.beaconcancer.org/index.php?title=Cancer_Centers Go back to Cancer Centers list.] | | [https://wiki.beaconcancer.org/index.php?title=Cancer_Centers Go back to Cancer Centers list.] |
| | | {{#set: |
| [[Estonia|See other cancer centers in Estonia.]] | | [[hasCoordinates::59.398689, 24.701547]] |
| <!--
| | }} |
| Source:
| | == [[hasClinicalTrial::Trials_(North_Estonia_Medical_Centre)|Trials]] == |
| [https://www.regionaalhaigla.ee/en]
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| -->
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| == Trials == | |
| <div class="mw-collapsible" data-expandtext="Show" data-collapsetext="Hide">
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| <div class="mw-collapsible-content">
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| <!--
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| '''[https://clinicaltrials.gov/ct2/show/NCT03104699?cond=Cancer&locn=%22North+Estonia+Medical+Centre%22&cntry=EE&lupd_s=10%2F21%2F2022&lupd_d=14 Study of AGEN2034 in Advanced Tumors and Cervical Cancer]'''
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| | |
| '''Summary:''' This is a 2-part trial: a Phase 1, open-label, dose-escalation study in subjects with metastatic or locally advanced solid tumors, with a consecutive Phase 2 expansion to evaluate efficacy in subjects with recurrent, unresectable, or metastatic (advanced) cervical cancer that has progressed after a platinum-based treatment regimen.
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| '''Sponsor, manager, or home institution:''' Agenus Inc.
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| '''Intervention/Treatment:''' Drug: AGEN2034
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| '''Number of patients:''' 211 participants
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| '''Beginning Date:''' April 7, 2017
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| '''Last Update:''' November 3, 2022
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| '''Recruitment Status:''' Completed.
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| '''Cancer areas of interest:''' Advanced Cancer and Cervical Cancer
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| '''[https://clinicaltrials.gov/ct2/show/NCT04241185?cond=Cancer&locn=%22North+Estonia+Medical+Centre%22&cntry=EE&lupd_s=10%2F21%2F2022&lupd_d=14 Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Chemoradiotherapy (CRT) Versus CRT Alone in Muscle-invasive Bladder Cancer (MIBC) (MK-3475-992/KEYNOTE-992)]'''
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| '''Summary:''' This study is designed to assess the antitumor efficacy and safety of pembrolizumab in combination with chemoradiotherapy (CRT) versus CRT alone in participants with muscle-invasive bladder cancer (MIBC). The primary hypothesis is that pembrolizumab + chemoradiotherapy is superior to placebo + chemoradiotherapy with respect to bladder intact event-free survival.
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| '''Sponsor, manager, or home institution:''' Merck Sharp & Dohme LLC
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| '''Intervention/Treatment:''' Drug: Pembrolizumab;
| |
| Radiation: Conventional Radiotherapy (Bladder only);
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| Radiation: Conventional Radiotherapy (Bladder and pelvic nodes);
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| Radiation: Hypofractionated Radiotherapy (Bladder only);
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| Drug: Cisplatin;
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| Drug: Fluorouracil (5-FU);
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| Drug: Mitomycin C (MMC);
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| Drug: Gemcitabine;
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| Drug: Placebo to Pembrolizumab
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| | |
| '''Number of patients:''' 636 participants
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| | |
| '''Beginning Date:''' January 27, 2020
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| '''Last Update:''' October 21, 2022
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| '''Recruitment Status:''' Recruiting.
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| | |
| '''Cancer areas of interest:''' Urinary Bladder Neoplasms
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| -->
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| </div> | | </div> |
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|
| == [[hasExperts::Experts_(North_Estonia_Medical_Centre)|Experts]] == | | == [[hasExperts::Experts_(North_Estonia_Medical_Centre)|Experts]] == |
| <div class="mw-collapsible" data-expandtext="Show" data-collapsetext="Hide"> | | <div class="mw-collapsible" data-expandtext="Show" data-collapsetext="Hide"> |
| '''[https://www.regionaalhaigla.ee/en/blood-establishment Blood Establishment]'''
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|
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| '''[https://www.regionaalhaigla.ee/en/chemotherapy Chemotherapy Centre]'''
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|
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| '''[https://www.regionaalhaigla.ee/en/department-2-follow-care Department of Follow-Up Care - Oncologic Care]'''
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|
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| '''[https://www.regionaalhaigla.ee/en/general-and-oncology-urology-centre General and Oncology Urology Centre]'''
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|
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| '''[https://www.regionaalhaigla.ee/en/general-surgery-and-oncology-surgery General Surgery and Oncology Surgery]'''
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|
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| '''[https://www.regionaalhaigla.ee/en/gynaecology-centre Gynaecology Centre]'''
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|
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| '''[https://www.regionaalhaigla.ee/en/haematology Haematology Centre]'''
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|
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| '''[https://www.regionaalhaigla.ee/en/head-and-neck-surgery-centre Head and Neck Surgery Centre]'''
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|
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| '''[https://onkoloogiakeskus.ee/laboratoorsed-uuringud Laboratory]'''
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|
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| '''[https://www.regionaalhaigla.ee/en/neurosurgery-centre Neurosurgery Centre]'''
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|
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| '''[https://www.regionaalhaigla.ee/en/nuclear-medicine Nuclear Medicine]'''
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|
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| '''[https://www.regionaalhaigla.ee/en/oncology-and-haematology-policlinic Oncology and Haematology Policlinic]'''
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|
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| '''[https://www.onkoloogiakeskus.ee/palliatiivravi Pain and palliative care]'''
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|
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| '''[https://www.regionaalhaigla.ee/en/pathology Pathology Department]'''
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|
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| '''[https://www.onkoloogiakeskus.ee/palliatiivravi Psychologists]'''
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|
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| '''[https://www.regionaalhaigla.ee/en/radiology Radiology Department]'''
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|
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| '''[https://www.regionaalhaigla.ee/en/radiotherapy-centre Radiotherapy Centre]'''
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|
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| '''[https://www.onkoloogiakeskus.ee/palliatiivravi Social Workers]'''
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|
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| '''[https://www.onkoloogiakeskus.ee/palliatiivravi Spiritual Care]'''
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| </div> | | </div> |
|
| |
|
| == Learning Resources == | | == Learning Resources == |
| <div class="mw-collapsible" data-expandtext="Show" data-collapsetext="Hide"> | | <div class="mw-collapsible" data-expandtext="Show" data-collapsetext="Hide"> |
| === [[hasTraining::Professional_Training_(North_Estonia_Medical_Centre)|Professional Training]] === | | === [[hasTraining::Trainings:_Professional_Training_(North_Estonia_Medical_Centre)|Trainings: Professional Training]] === |
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| '''Content type:''' Provides training to professionals.
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| '''Target audience:''' Doctors, nurses and care staff and other professionals of health from across Estonia.
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| '''Access:''' Information [https://koolitus.regionaalhaigla.ee/].
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| </div> | | </div> |
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| == [[hasNovelTherapiesandDiagnosticMethods::Novel_Therapies_and_Diagnostic_Methods_(North_Estonia_Medical_Centre)|Novel Therapies and Diagnostic Methods]] == | | == [[hasHospitalCapacityInfo::Novel_Therapies_and_Diagnostic_Methods_(North_Estonia_Medical_Centre)|Novel Therapies and Diagnostic Methods]] == |
| <div class="mw-collapsible" data-expandtext="Show" data-collapsetext="Hide"> | | <div class="mw-collapsible" data-expandtext="Show" data-collapsetext="Hide"> |
|
| |
| === Diagnostics ===
| |
|
| |
| {| class="wikitable"
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| ! Radiology !! !! !!
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| |-
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| | '''Type''' || '''Name''' || '''Availibility''' || '''Uses per year'''
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| |-
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| | Machine || CT scanners || 5 ||
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| |-
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| | Machine || MRI (specify the strength and field of the techniques) || 3 || 14,283
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| |-
| |
| | Machine || Mammography (please specify analogic mammography or digital) || yes (digital) ||
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| |-
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| | Machine || Ultrasound || yes || 62,238
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| |-
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| | Machine || Gamma Camera || 1 ||
| |
| |-
| |
| | Machine || Radiation Therapy Devices || 5 || 1,600 patients (2020)
| |
| |-
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| | Machine || Angiograph || 5 ||
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| |-
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| | Technique || Radioisotope || yes || 2,434
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| |-
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| | Technique || MRI-guided biopsy || yes ||
| |
| |-
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| | Technique || X-rays || yes || 118,621
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| |-
| |
| | Technique || Stereostatic biopsy || yes ||
| |
| |-
| |
| | Technique || Ultrasound guided biopsy || yes ||
| |
| |-
| |
| | Technique || Endoscopic retrograde cholangiopancreatography (ERCP) || yes ||
| |
| |-
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| | Technique || CT guided biopsis || yes ||
| |
| |-
| |
| | Technique || Angiography || yes ||
| |
| |-
| |
| ! Nuclear Medicine !! !! !!
| |
| |-
| |
| | '''Type''' || '''Name''' || '''Availibility''' || '''Uses per year'''
| |
| |-
| |
| | Machine || Pet Scan || yes ||
| |
| |-
| |
| | Machine || PET (PET CT + PET MRI) || 1 ||
| |
| |-
| |
| | Machine || PET CT || yes ||
| |
| |-
| |
| | Machine || SPECT CT || yes ||
| |
| |-
| |
| | Technique || Sentinel node scintigraphy || yes ||
| |
| |-
| |
| ! Pathology !! !! !!
| |
| |-
| |
| | '''Type''' || '''Name''' || '''Availibility''' || '''Uses per year'''
| |
| |-
| |
| | Facility || Cytology laboratory || yes ||
| |
| |-
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| | Facility || Histopathology laboratory || yes ||
| |
| |-
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| | Technique || FISH (Fluorescence In Situ Hybridization) || yes ||
| |
| |-
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| | Technique || PCR (Polymerase Chain Reaction) || yes ||
| |
| |-
| |
| ! Pathology: Molecular Tests !! !! !!
| |
| |-
| |
| | '''Type''' || '''Name''' || '''Availibility''' || '''Uses per year'''
| |
| |-
| |
| | Technique || PGR || yes ||
| |
| |-
| |
| | Technique || KI-67 || yes ||
| |
| |-
| |
| | Technique || PDL1 || yes ||
| |
| |-
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| | Technique || ER || yes ||
| |
| |-
| |
| | Technique || KRAS || yes ||
| |
| |-
| |
| | Technique || BRAF || yes ||
| |
| |-
| |
| | Technique || EGFR || yes ||
| |
| |-
| |
| | Technique || ALK || yes ||
| |
| |-
| |
| | Technique || ROS || yes ||
| |
| |-
| |
| | Technique || HER2 status || yes ||
| |
| |-
| |
| ! Others !! !! !!
| |
| |-
| |
| | '''Type''' || '''Name''' || '''Availibility''' || '''Uses per year'''
| |
| |-
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| | Technique || Bronchoscopy || yes ||
| |
| |-
| |
| | Technique || Hysteroscopy || yes ||
| |
| |-
| |
| | Technique || Video dermatoscopy || yes ||
| |
| |}
| |
|
| |
| === Treatment ===
| |
|
| |
| {| class="wikitable"
| |
| ! Surgical Oncology !! !! !!
| |
| |-
| |
| | '''Type''' || '''Name''' || '''Availibility''' || '''Uses per year'''
| |
| |-
| |
| | Specialist || Breast surgery || yes ||
| |
| |-
| |
| | Specialist || Urological surgery || yes ||
| |
| |-
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| | Specialist || Thoracic surgery || yes ||
| |
| |-
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| | Specialist || Digestive surgery || yes ||
| |
| |-
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| | Specialist || Neurosurgery || 8 ||
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| |-
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| | Specialist || Gynaecological surgery || yes ||
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| |-
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| | Specialist || Head and neck surgery || yes ||
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| |-
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| | Specialist || Soft tissue surgery || yes ||
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| |-
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| | Specialist || Oncoplastic surgery || yes ||
| |
| |-
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| | Specialist || ENT surgery || yes ||
| |
| |-
| |
| ! Radiotherapy !! !! !!
| |
| |-
| |
| | '''Type''' || '''Name''' || '''Availibility''' || '''Uses per year'''
| |
| |-
| |
| | Machine || Linear accelerators with IMRT/VMAT || yes ||
| |
| |-
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| | Machine || Linear accelerators with IGRT || yes ||
| |
| |-
| |
| | Machine || Linear accelerators with SBRT/SRS || 2 ||
| |
| |-
| |
| | Machine || Brachytherapy unit || yes || 400 (2020)
| |
| |-
| |
| | Technique || Intraperitoneal chemo-hyperthermia ( HIPEC) || yes ||
| |
| |-
| |
| | Technique || Treatment Planning System || yes ||
| |
| |-
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| | Technique || Chemoembolization || yes ||
| |
| |-
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| | Technique || Thermal ablation (with radiofrequency or microwave) || yes ||
| |
| |-
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| | Technique || 4D Radiotherapy planning for lung tumors || yes ||
| |
| |-
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| | Technique || 3D conformal radiotherapy || yes ||
| |
| |-
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| | Technique || Radiosurgery || yes ||
| |
| |-
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| | Technique || Proton therapy || yes || 21,300 (2020)
| |
| |-
| |
| | Technique || Respiratory motion management || yes ||
| |
| |-
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| | Technique || Conventional simulation || yes ||
| |
| |-
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| | Technique || CT planning || yes ||
| |
| |-
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| | Technique || Magnetic resonance for radiotherapy treatment planning || yes ||
| |
| |-
| |
| | Technique || PET CT treatment planning || yes ||
| |
| |-
| |
| ! Hemato-Oncology / Bone Marrow Transplants !! !! !!
| |
| |-
| |
| | '''Type''' || '''Name''' || '''Availibility''' || '''Uses per year'''
| |
| |-
| |
| | Facility || Bone marrow / stem cell bank || yes ||
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| |-
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| | Facility || Cellular therapy unit with GMP (Good Manufacturing Practice) || yes ||
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| |-
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| | Technique || Autologous stem cell transplants || yes ||
| |
| |-
| |
| ! Specialists !! !! !!
| |
| |-
| |
| | '''Type''' || '''Name''' || '''Availibility''' || '''Uses per year'''
| |
| |-
| |
| | Specialist || Physician with a specialisation in palliative care || 1 ||
| |
| |-
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| | Specialist || Medical oncologist || yes ||
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| |-
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| | Specialist || Nurse with a specialisation/certification in palliative care || yes ||
| |
| |-
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| | Specialist || Nurse with a specialization/certification in oncology || yes ||
| |
| |-
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| | Specialist || Physician specialised in pain treatment || 2 ||
| |
| |-
| |
| | Specialist || Radiotherapist || yes || 11,500 appointments (2020)
| |
| |-
| |
| | Specialist || Psychologist or Psychotherapist || 3 ||
| |
| |-
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| | Specialist || Social worker || yes ||
| |
| |-
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| | Specialist || Spiritual care || yes ||
| |
| |-
| |
| | Specialist || Physiotherapist || yes ||
| |
| |-
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| | Specialist || Dietitian || yes ||
| |
| |-
| |
| ! Others !! !! !!
| |
| |-
| |
| | '''Type''' || '''Name''' || '''Availibility''' || '''Uses per year'''
| |
| |-
| |
| | Technique || Embolization with microparticles || yes ||
| |
| |-
| |
| | Facility || Phase 1 Clinical Trial Unit || yes
| |
| |}
| |
|
| |
| === Prevention ===
| |
|
| |
| {| class="wikitable"
| |
| ! Screening and Others !! !! !!
| |
| |-
| |
| | '''Type''' || '''Name''' || '''Availibility''' || '''Uses per year'''
| |
| |-
| |
| | Facility || Breast cancer screening program || yes ||
| |
| |-
| |
| | Facility || Cervical cancer screening program || yes ||
| |
| |-
| |
| | Facility || Colorectal cancer screening program || yes ||
| |
| |-
| |
| | Facility || Smoking detoxification center || yes
| |
| |}
| |
|
| |
| === Quality of Life ===
| |
|
| |
| {| class="wikitable"
| |
| ! Quality of Life !! !! !!
| |
| |-
| |
| | '''Type''' || '''Name''' || '''Availibility''' || '''Uses per year'''
| |
| |-
| |
| | Facility || Supportive care unit || yes
| |
| |}
| |
|
| |
| === Palliative Care ===
| |
|
| |
| {| class="wikitable"
| |
| ! Others !! !! !!
| |
| |-
| |
| | '''Type''' || '''Name''' || '''Availibility''' || '''Uses per year'''
| |
| |-
| |
| | Facility || Home palliative care availability || yes
| |
| |}
| |
|
| |
| </div> | | </div> |
|
| |
|
| == Cancer-related Patient Associations and Resources == | | == Cancer-related Patient Associations and Resources == |
| <div class="mw-collapsible" data-expandtext="Show" data-collapsetext="Hide"> | | <div class="mw-collapsible" data-expandtext="Show" data-collapsetext="Hide"> |
|
| |
| === [[hasPatientResource::Counsil:_Patient_Advisory_Council_(North_Estonia_Medical_Centre)|Counsil: Patient Advisory Council]] ===
| |
|
| |
| '''Content Type:''' Ensures the interests of the patient are being taken into account when making decisions and designing services, and that the patient has an active role in the treatment process.
| |
|
| |
| '''Members:''' Estonian Rheumatism Association; Avitus NGO; Estonian Inflammatory Bowel Disease Society NGO; Estonian Celiac Society;
| |
| Estonian Psoriasis Association; Estonian Hemophilia Society;Estonian Chamber of Disabled People; Tallinn Chamber of Disabled People;
| |
| Saaremaa Cancer Society; Läänemaa Cancer Association; Estonian Stroke Patients Society.
| |
|
| |
| '''Access:''' Information [https://www.regionaalhaigla.ee/et/patsiendinoukoda].
| |
|
| |
|
| === [[hasPatientResource::Resource:_Learning_Resources_for_Relatives_and_Caretakers_(North_Estonia_Medical_Centre)|Resource: Learning Resources for Relatives and Caretakers]] === | | === [[hasPatientResource::Resource:_Learning_Resources_for_Relatives_and_Caretakers_(North_Estonia_Medical_Centre)|Resource: Learning Resources for Relatives and Caretakers]] === |
|
| |
| '''Content Type:''' Guides and counseling appointment information.
| |
|
| |
| '''Target Audience:''' Patients, relatives and caretakers.
| |
|
| |
| '''Access:''' Information [https://onkoloogiakeskus.ee/lahedasele].
| |
|
| |
|
| === [[hasPatientResource::Resource:_Trials_Information_for_Patients_(North_Estonia_Medical_Centre)|Resource: Trials Information for Patients]] === | | === [[hasPatientResource::Resource:_Trials_Information_for_Patients_(North_Estonia_Medical_Centre)|Resource: Trials Information for Patients]] === |
|
| |
| '''Primary Purpose:''' Instructs about the procedure to participate in one of the hospital's clinical trials.
| |
|
| |
| '''Target Audience:''' Oncological patients.
| |
|
| |
| '''Access:''' Information [https://www.regionaalhaigla.ee/en/clinical-trials].
| |
|
| |
|
| === [[Service:_Chemotherapy_Counseling_(North_Estonia_Medical_Centre)|Service: Chemotherapy Counseling]] === | | === [[Service:_Chemotherapy_Counseling_(North_Estonia_Medical_Centre)|Service: Chemotherapy Counseling]] === |
|
| |
| '''Content Type:''' A nurse-counselor instructs the patient and his family individually before, during, and after the chemotherapy treatment about the procedure, possible side effects, and how to deal with those.
| |
|
| |
| '''Target Audience:''' Patients and their relatives.
| |
|
| |
| '''Access:''' Information [https://onkoloogiakeskus.ee/keemiaravi-noustamine].
| |
|
| |
|
| === [[hasPatientResource::Service:_Palliative_Care_Nurse_Advisor_(North_Estonia_Medical_Centre)|Service: Palliative Care Nurse Advisor]] === | | === [[hasPatientResource::Service:_Palliative_Care_Nurse_Advisor_(North_Estonia_Medical_Centre)|Service: Palliative Care Nurse Advisor]] === |
|
| |
|
| '''Content Type:''' A nurse instructs about the disease the patient is suffering from and how to deal with it and connects the patient to specialists who will help with palliative care.
| | === [[hasPatientResource::Service:_Tobacco_Cessation_Counseling_Office_(North_Estonia_Medical_Centre)|Service: Tobacco Cessation Counseling Office]] === |
| | </div> |
|
| |
|
| '''Target Audience:''' Patients and their relatives.
| | __NOTOC__ |
| | | <span style="display:none">hasCoordinates::59.398689, 24.701547</span> |
| '''Access:''' Information [https://www.onkoloogiakeskus.ee/palliatiivravi].
| | <span style="display:none">hasClinicalTrial::Trials_(North_Estonia_Medical_Centre)|Trials</span> |
| | | <span style="display:none">hasExperts::Experts_(North_Estonia_Medical_Centre)|Experts</span> |
| === [[Service: Tobacco Cessation Counseling Office (North Estonia Medical Centre)]] === | | <span style="display:none">hasTraining::Trainings:_Professional_Training_(North_Estonia_Medical_Centre)|Trainings: Professional Training</span> |
| | | <span style="display:none">hasHospitalCapacityInfo::Novel_Therapies_and_Diagnostic_Methods_(North_Estonia_Medical_Centre)|Novel Therapies and Diagnostic Methods</span> |
| '''Content Type:''' Trained nurses perform counseling, organize a treatment plan for the patients, and accompany them during a specific time to help them quit smoking.
| | <span style="display:none">hasPatientResource::Resource:_Learning_Resources_for_Relatives_and_Caretakers_(North_Estonia_Medical_Centre)|Resource: Learning Resources for Relatives and Caretakers</span> |
| | | <span style="display:none">hasPatientResource::Resource:_Trials_Information_for_Patients_(North_Estonia_Medical_Centre)|Resource: Trials Information for Patients</span> |
| '''Target Audience:''' Free for everyone.
| | <span style="display:none">hasPatientResource::Service:_Palliative_Care_Nurse_Advisor_(North_Estonia_Medical_Centre)|Service: Palliative Care Nurse Advisor</span> |
| | | <span style="display:none">hasPatientResource::Service:_Tobacco_Cessation_Counseling_Office_(North_Estonia_Medical_Centre)|Service: Tobacco Cessation Counseling Office</span> |
| '''Access:''' Information [https://onkoloogiakeskus.ee/suitsetamisest-loobumine].
| | <span style="display:none">hasCancerType::C00-D48: All neoplasms</span> |
| </div> | | <span style="display:none">hasCancerType::C00-C97: All cancer types</span> |
| | <span style="display:none">hasCancerType::C00-C14: Mouth/throat cancers</span> |
| | <span style="display:none">hasCancerType::C15-C26: Digestive system cancers</span> |
| | <span style="display:none">hasCancerType::C30-C39: Lung/chest cancers</span> |
| | <span style="display:none">hasCancerType::C40-C41: Bone cancers</span> |
| | <span style="display:none">hasCancerType::C43-C44: Skin cancers/melanoma</span> |
| | <span style="display:none">hasCancerType::C45-C49: Soft tissue cancer</span> |
| | <span style="display:none">hasCancerType::C50: Breast cancer</span> |
| | <span style="display:none">hasCancerType::C51-C58: Female genitalia cancers</span> |
| | <span style="display:none">hasCancerType::C60-C63: Male genitalia cancer</span> |
| | <span style="display:none">hasCancerType::C64-C68: Urinary system cancers</span> |
| | <span style="display:none">hasCancerType::C69-C72: Eye and brain cancer</span> |
| | <span style="display:none">hasCancerType::C73-C75: Thyroid and other gland cancers</span> |
| | <span style="display:none">hasCancerType::C76-C80: Cancers of unknown or unspecified areas</span> |
| | <span style="display:none">hasCancerType::C81-C96: Cancers of the blood and immune system</span> |
| | <span style="display:none">hasCancerType::C97-C97: Cancers in multiple locations from the start</span> |
| | <span style="display:none">hasCancerType::D00-D09: Early-stage cancers not yet spread</span> |
| | <span style="display:none">hasCancerType::D10-D36: Benign tumour</span> |
| | <span style="display:none">hasCancerType::D37-D48: Growths of uncertain nature</span> |
| | <span style="display:none">hasCancerType::unknown</span> |