North Estonia Medical Centre: Difference between revisions

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== [[North Estonia Medical Centre OECI Criteria Compliance]] ==
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== [[Trials]] ==
== [[Trials]] ==

Revision as of 20:21, 21 November 2022

The North Estonia Medical Centre is one of the top healthcare providers in the country. Its statutes states that their goal is "to provide high-quality, specialized medical care and ambulance services, to be the learning base of training that precedes and follows the acquiring of health care professionals’ qualifications and does healthcare-related study and research work."

North Estonia Medical Centre OECI Criteria Compliance

Trials

Study of AGEN2034 in Advanced Tumors and Cervical Cancer

Summary: This is a 2-part trial: a Phase 1, open-label, dose-escalation study in subjects with metastatic or locally advanced solid tumors, with a consecutive Phase 2 expansion to evaluate efficacy in subjects with recurrent, unresectable, or metastatic (advanced) cervical cancer that has progressed after a platinum-based treatment regimen.

Sponsor, manager, or home institution: Agenus Inc.

Intervention/Treatment: Drug: AGEN2034

Number of patients: 211 participants

Beginning Date: April 7, 2017

Last Update: November 3, 2022

Recruitment Status: Completed.

Cancer areas of interest: Advanced Cancer and Cervical Cancer

Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Chemoradiotherapy (CRT) Versus CRT Alone in Muscle-invasive Bladder Cancer (MIBC) (MK-3475-992/KEYNOTE-992)

Summary: This study is designed to assess the antitumor efficacy and safety of pembrolizumab in combination with chemoradiotherapy (CRT) versus CRT alone in participants with muscle-invasive bladder cancer (MIBC). The primary hypothesis is that pembrolizumab + chemoradiotherapy is superior to placebo + chemoradiotherapy with respect to bladder intact event-free survival.

Sponsor, manager, or home institution: Merck Sharp & Dohme LLC

Intervention/Treatment: Drug: Pembrolizumab; Radiation: Conventional Radiotherapy (Bladder only); Radiation: Conventional Radiotherapy (Bladder and pelvic nodes); Radiation: Hypofractionated Radiotherapy (Bladder only); Drug: Cisplatin; Drug: Fluorouracil (5-FU); Drug: Mitomycin C (MMC); Drug: Gemcitabine; Drug: Placebo to Pembrolizumab

Number of patients: 636 participants

Beginning Date: January 27, 2020

Last Update: October 21, 2022

Recruitment Status: Recruiting.

Cancer areas of interest: Urinary Bladder Neoplasms

Experts

Learning Resources

Patient School

Content Type: E-courses and lectures.

Target Audience: For everyone.

"Chest Cabinet"

Content Type: Local support for concerns on breast cancer.

Target Audience: Women of all ages.

Learning Resources for Relatives and Caretakers

Content Type: Guides and counseling appointment information.

Target Audience: Patients, Relatives and Caretakers.

Other Learning Materials

Cancer-related Patient Associations

Patient Advisory Council

Primary Purpose: To ensure the interests of the patient are being taken into account when making decisions and designing services, and that the patient has an active role in the treatment process.

Members: Estonian Rheumatism Association; Avitus NGO; Estonian Inflammatory Bowel Disease Society NGO; Estonian Celiac Society; Estonian Psoriasis Association; Estonian Hemophilia Society; Estonian Chamber of Disabled People; Tallinn Chamber of Disabled People; Saaremaa Cancer Society; Läänemaa Cancer Association; Estonian Stroke Patients Society.