FISH (Fluorescence In Situ Hybridization)

Fluorescence In Situ Hybridization (FISH) is an advanced molecular technique used to identify and visualize specific DNA sequences within chromosomes. By using fluorescently labeled probes that bind to particular genetic regions, FISH can detect and localize genetic abnormalities such as duplications, deletions, or translocations that may be associated with cancers and genetic disorders. The fluorescent signals are viewed under a specialized microscope, providing clear, precise images of the genetic material. This technique is crucial for diagnosing conditions like leukemia, breast cancer, and genetic syndromes, guiding targeted treatments and personalized medicine. FISH is highly accurate, offering detailed insights that enhance our understanding of genetic diseases and contribute to more effective patient care.