EGFR

EGFR, or Epidermal Growth Factor Receptor, is a protein found on the surface of cells that helps regulate cell growth, survival, and division. Mutations and overexpression of the EGFR gene are common in various cancers, particularly non-small cell lung cancer, glioblastoma, and head and neck cancers. These alterations lead to continuous activation of the EGFR protein, promoting uncontrolled cell proliferation and tumour development. Identifying EGFR mutations in tumours is crucial for determining the most effective treatment strategies, as targeted therapies, such as EGFR inhibitors, can specifically block this pathway and inhibit cancer growth. Understanding EGFR's role in cancer allows for personalized treatment plans, improving patient outcomes through more precise and effective therapeutic interventions.